This handbook is designed to provide the radiation oncologist with clear practical guidance in the delineation of tumor volumes and/or radiation fields for a wide variety of pediatric cancers, including all of the most frequently encountered malignancies of childhood. These treatment fields and volumes may be utilized in the delivery of conformal therapies such as intensity-modulated radiation therapy and proton therapy, the latter being particularly relevant in children. Each chapter focuses on a specific tumor type, providing general guidelines that will assist the reader in delineating the clinical target volume for particular presentations, including patterns of spread. As the target volumes can be complex, detailed illustrations are presented of the volumes in representative cases, contoured slice by slice on the planning CT images. In addition to target volume delineation for conformal treatment, field design setup for conventional approaches is also discussed. 

Dr. Terezakis is an associate professor of radiation oncology and director of pediatric radiation oncology at the Johns Hopkins School of Medicine. Her clinical research has been focused on the optimization of modern therapies for pediatric cancers, particularly bone and soft tissue sarcomas, CNS tumors, and lymphomas.

Dr. MacDonald is an associate professor of radiation oncology at Harvard Medical School, and a radiation oncologist at the Massachusetts General Hospital.  Her research focuses on the optimal use of proton radiotherapy for pediatric malignancies and young women with breast cancer and minimizing side effects of cancer therapies.